Explore U.S. Route 64, a scenic and historic highway stretching from North Carolina’s Outer Banks to New Mexico’s high desert. Discover key cities, attractions, and travel highlights along this iconic east-west route.
U.S. Route 64 is a major east–west highway spanning approximately 2,300 miles across the southern and central United States. It begins in the scenic Outer Banks of North Carolina at Whalebone Junction and stretches westward all the way to the Arizona border in northeast New Mexico, just east of the town of Teec Nos Pos. Along its path, US 64 passes through a diverse array of landscapes, including coastal plains, the Appalachian Mountains, fertile farmland, and desert mesas.
The highway serves as a vital connector through six states: North Carolina, Tennessee, Arkansas, Oklahoma, New Mexico, and a brief portion of eastern Arizona. In the eastern states, US 64 closely parallels major interstates like I-40 but often provides a more scenic or locally accessible alternative. In the west, especially through Oklahoma and New Mexico, it cuts through rural areas and tribal lands, including a picturesque stretch through the Cimarron Canyon and the Sangre de Cristo Mountains.
U.S. Route 64 intersects with numerous important routes, including I-75 in Tennessee, I-35 in Oklahoma, and US 285 in New Mexico. Its role as a regional thoroughfare is enhanced by its proximity to natural and cultural attractions such as the Great Smoky Mountains, Memphis, the Ozarks, and Taos. This blend of utility and charm makes US 64 a favorite for both long-haul drivers and road-tripping travelers seeking a less-traveled path across the heart of America.
Cruise 7 miles along historic U.S. Highway 64 from Van Buren to Fort Smith, Arkansas. Cross the Arkansas River twice, explore downtown charm, and pass iconic landmarks like the Fort Smith National Historic Site and Miss Laura’s Visitor Center before crossing into Okla…
Cruise U.S. Highway 64 from Alma to Van Buren, Arkansas — a short drive showcasing rolling farmland, busy commercial corridors, and the charm of historic downtown Van Buren.
Travel 17 miles west along U.S. Highway 64 from Marion to Earle, Arkansas, through the fertile Delta farmland of Crittenden County. Pass through Crawfordsville and explore small-town Arkansas along this historic stretch of highway.
Take a scenic road trip along U.S. Highway 64 from Ozark to Russellville, Arkansas. This 49-mile drive passes through historic wine country, quiet towns, and alongside Lake Dardanelle—showcasing the Arkansas River Valley’s charm and character.
Travel east along U.S. Highway 64 from Alma to Ozark, Arkansas on a 24-mile journey through farmland, forest, and historic towns nestled in the scenic Arkansas River Valley.
Explore western Arkansas with this 73-mile road trip along U.S. Highway 64 from Russellville to Alma. Cross Lake Dardanelle, pass through Clarksville, Altus, and Ozark, and discover scenic backroads, vineyards, and historic towns just off I-40.
Drive 10 miles west along U.S. Route 70 (Summer Avenue) from Bartlett to Memphis, Tennessee. Follow this historic urban corridor through neighborhoods, commercial zones, and gritty mid-century Americana in the heart of Memphis.
Cruise 6 miles west on U.S. Route 64 from Lakeland to Bartlett, TN. Pass I-40 and Wolfchase before ending at US-70/US-79. Suburban growth meets highway convenience on this short Memphis metro drive.
Drive 9 miles west on U.S. Route 64 through Tulsa, Oklahoma—from eastern suburbs through rail-lined corridors and into the heart of downtown before merging onto I-244.
Take a relaxed drive along U.S. Route 64 from Morrilton to Conway, Arkansas. This 21-mile route passes through Plumerville and Menifee, showcasing small-town charm, farmland, and local history before arriving in Conway near Hendrix College and I-40.
Take a scenic 26-mile drive along U.S. Route 64 from Russellville to Morrilton, Arkansas. This journey through Pottsville and Atkins highlights the Arkansas River Valley’s agricultural roots, small-town charm, and local roadside legends.